这个等位基因是由Dmdtm1Khan产生的。通过在正确靶向的ES细胞中短暂表达Cre重组酶,整段2.4 Mb的Dmd基因被移除。RT-PCR和 Western blot 检测在肌肉、大脑和小脑中未发现全长和短形式的表达(来源:J:96210)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
基因内删除
--
1
18
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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