在exon 1的3'末端、intron 1以及exon 2的5'端插入了一个IRES-Betagal-MC-neo cassette,取代了这些区域。删除的序列编码了膜蛋白1和2,以及包含的区域。RT-PCR证实了这个变异等位基因是无功能的。(来源:J:96442)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
6
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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