一个neo基因替换了编码膜段D2-D4的5和6号外显子,这在突变大脑组织部分的 Western blot 检测中证实了没有蛋白质存在。(来源:J:96311)
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A neo replaced exons 5 and 6, which encode transmembrane segments D2-D4. Western blot of mutant brain tissue fractions confirmed the absence of protein. (J:96311)