这个转基因载体包含4.8千碱基的猪酪氨酸羟化酶(Th)启动子序列,一段携带C88G突变的人类α-synuclein(SNCA)基因编码区,该突变导致阿尔法30 Pro氨基酸替换,以及SV40的polyadenylation序列。(来源:J:70209)
Basic Information
Swiss Webster x (C57BL/6 x DBA)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count