这个转基因包含了4.5千碱基的猪酪氨酸羟化酶(Th)启动子序列,一段编码阿尔茨海默病相关的人类α-synuclein(SNCA)的突变Ala30Pro氨基酸的cDNA,以及SV40小t剪接位点和SV40polyadenylation序列。(来源:J:69529)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(DBA x C57BL/6)F1
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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