Exon 1和2被替换成lacZ-neo cassette。通过在肝脏和肾脏提取物中进行 Western blot 分析,确认了没有蛋白质产物产生。(来源:J:131376)
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Exon 1 and 2 were replaced with a lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on liver and kidney extracts. (J:131376)