设计了一个靶向构建,它在exon 5的两侧插入了loxP位点,并包含一个FRT引导的序列,该序列带有所有三个阅读框的终止子、一个内含子-绿色荧光蛋白-neo。通过流式细胞术确认了产生二顺式mRNA的转录。(来源:J:95651)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
--
1
2
14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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