这个转基因表达的是人类源BCR/ABL融合蛋白的P230变体,其中BCR的第19外显子与ABL的第2外显子融合。该基因是通过小鼠胚胎干细胞病毒(MSCV)的LTR序列克隆下来的,原文中称为PCMV。携带这种等位基因的老鼠体内整合了5个转基因拷贝。(来源:J:84626)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NCrj
--
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部