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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Agrp
tm2(HBEGF)Rpa
Alias:
Agrp
tm2(DTR)Rpa
Agrp
DTR
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基础信息
表型特征
文献报道
将人型白喉毒素受体,随后是带有IRES-DsRed2报告基因的区域,靶向到Agrp基因位点,以实现这些细胞的条件性杀灭。通过小鼠的生殖细胞,cre介导的重组被用来去除neo cassette(来源:J:132360)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3527177
129S4/SvJaeSor
Targeted
插入
--
1
1
17
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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