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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Chka
Gt(XH252)Byg
Alias:
Chka
-
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基础信息
表型特征
文献报道
将含有β-geo融合的pGT1Lxf基因陷阱载体插入到第五内含子中。通过杂合小鼠肝脏和睾丸提取物的 Western blot 分析,证实了蛋白质产量的降低。作者称这为一个无功能等位基因。(来源:J:130726)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3526395
129P2/OlaHsd
Gene trapped
基因捕获载体的插入
--
1
2
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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