与Cre删除小鼠杂交剔除了包含启动子和外显子1的敲除区域。脾脏细胞总提取物的 Western blot 显示突变体中缺乏蛋白质。(来源:J:95215)
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Crossing with cre deleter mice excised the floxed region containing the promoter and exon 1. Western blot of spleen whole cell lysates demonstrated a lack of protein in mutants. (J:95215)