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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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基因编辑小鼠
Nfkbiz
tm1Mamo
Alias:
MAIL
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基础信息
表型特征
文献报道
使用了一种靶向载体,替换掉了4号外显子的大部分以及5到8号的所有外显子,这部分编码了ankyrin重复I和II的部分,然后插入了一个neo标记,并在起始密码子下游位置加入了一个终止密码子突变。(来源:J:95040)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3525252
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入,基因内删除
--
1
--
6
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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