在 intron 1 处插入了一段带有 loxP 立即序列的耐药性基因,然后在 exon 2 中引入了第三个 loxP 立即序列。与 EIIa-cre 小鼠杂交导致 neo 基因被剔除,留下 exon 2 包含 loxP 立即序列。(来源:J:94911)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
1
89

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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