设计了一个靶向载体,用于插入经过改造的人胎盘碱性磷酸酶报告序列,以及在exon 1的ATG处带有polyA信号。对突变的MEFs进行了RT-PCR和 Western blot分析,结果显示了mRNA或蛋白质的表达(来源:J:96106)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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