在exon 1的起始甲硫氨酸密码子5'处插入了LoxP位点,随后在intron 2中插入了可剔除的诺卡因抗性基因和EGFP基因。与Cre-删除小鼠杂交导致诺卡因抗性基因被剔除,留下部分被剔除的exon 1和exons 2。EGFP插入是功能缺失的。(来源:J:94941)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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