This transgene contains the MMTV LTR (mouse mammary tumor virus long terminal repeat) fused to the HPV16 E6 and E7 orf sequences. The polyA tail is from SV40. Mice possessed 4-5 copies of the transgene oriented in tandom head to tail fashion. The transgene followed Mendelian inheritance patterns. The transgene was inherited in Mendelian fashion. (J:93826)