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中文
设计了一种靶向载体，用于将第一编码外显子替换为携带Y1227F突变的鼠Erbb2 cDNA，从而丧失Shc1的直接结合位点。还插入了neo序列。RT-PCR产物分析显示，突变体仅表达鼠cDNA。（来源：J:94397）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
