这个是一个通过在内含子1插入一个loxP-标记的neo,以及在内含子11增加第三个loxP位点创建的隐性等位基因。neo导致内含子1的剪接异常,使得大部分突变小鼠中有13-20%的转录本正常剪接。(来源:J:94582)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
11
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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