ENU诱变产生了18号外显子的一个点突变(C转T),导致谷氨酰胺被终止密码子取代。 Western blot结果显示睾丸、大脑和心脏中没有蛋白质表达。(来源:199215)
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ENU mutagenesis induced a point mutation (C to T) in exon 18 that results in the amino acid substitution of a stop codon for glutamine. Western blot analysis confirmed the absence of protein expression in the testes, brain and heart. (J:199215)