这个转基因表达的是小鼠H2-K b类I变异体,来源于一个7.5kb的基因克隆。克隆中插入了休眠的150bp loxP位点,分别位于exon 1的Hinc II酶切位点5'端和intron 3的Bam HI酶切位点内。构建的3'端有一个74bp的尾巴,包含HSV-1胸苷激酶基因的5'端。(来源:J:87648)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD
--
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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