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中文
带有Lattm2.1Mal突变基因的ES细胞被进一步选中，对酪氨酸密码子136进行替换，变为苯丙氨酸（p.Y136F）。 Western blot结果显示，突变小鼠胸腺细胞中的蛋白质含量与野生型相当。在9和10号外显子之间插入了floxed neo，随后通过与去失性小鼠杂交来移除这一序列（J:94074）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
