在4号和5号外显子,编码部分锌和底物结合位点的区域,被替换了 neo抗药性基因。突变肝样本的RT-PCR结果显示重组成功,与野生型相比,带宽缩短了200bp,这相当于4号和5号外显子的长度。proCPR-(J:93733)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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