E1-T147转基因构建时,包含了4.3kb的鼠弹性酶1(Ela1或E1)基因上游调控区、LTR稳定器以及SV40晚期16S的剪接位点,所有这些都在Simian病毒40的大T抗原(TAg)编码1-147氨基酸(包括在第148位插入了终止密码子)和polyA序列的上游。T1-147转基因小鼠(来源于289号创始株)已经建立。(引用:J:78026)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(B6D2F1/J x C57BL/6)
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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