一个新构建的cassette替换了包含所有五个外显子的4.8kb片段。RT-PCR、免疫组化和 Western blot 分析证实小肠(jejunum)和肠黏膜肥大细胞中无RNA,以及小肠(jejunum)和耳郭(ear pinna)中无蛋白质存在。(来源:J:93795)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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