Fv4^r

This allele, associated with natural resistance to infection by ecotropic Friend murine leukemia virus (FLV, MuLV) and Murine sarcoma virus, was identified in several wild mouse populations in Japan, Southeast Asia and western North America. Sequencing demonstrated that the allele contains ecotropic MuLV-related proviral sequence beginning in the C-terminal end of the pol region and extending through the env region and the 3' long terminal repeat. (J:7952)