转基因中包含了完整的人源MCL1基因,包括内源性MCL1启动子。半同源转基因小鼠在骨髓、淋巴结、胸腺和脾脏(包括B细胞和T细胞群体)中表达出了人源MCL1。在肾脏、小肠、子宫、肺和肝脏中,检测到了微量的转基因表达。(来源:J:50604)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
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1
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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