在exon 10的终止密码子后,插入了一个IRES-Cre-FRT-neo-FRT的 cassette,然后将这个cassette插入到3' UTR中。与表达FLP-e的 mice杂交后,Neo被剪切掉了。这个插入并未影响Pax7的正常功能。(来源:J:93443)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
72

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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