将人类的RET9 cDNA和一个带有floxed neo标记的序列插入了内源性基因座的第1外显子。与携带Cre基因的雄性小鼠杂交后,neo标记被去除了。RT-PCR结果显示,大脑中检测到了突变等位基因的表达。(来源:J:93262)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
23
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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