转基因中包含人类角蛋白14启动子,位于小鼠 baculoviral IAP 重复元件包含的5(Birc5)基因上游,长度为2.1kb,以及人类生长激素和polyadenylation序列,长度为2.2kb。转染表达特异性针对表皮和毛囊的角质细胞。建立了5个杂交瘤小鼠,选出了线19作为代表系。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F2
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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