在转暂时表达Cre重组酶后,Exon EDB(位于EIIIB)被删除,这剪除了包含neo抗性基因和该外显子的含floxed序列。对突变的MEFs进行的免疫印迹实验,使用抗EDB抗体检测,结果显示该外显子没有蛋白质表达。(来源:J:93250)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
基因内删除
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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