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中文
在第1内含子插入了floxed hygromycin cassette，然后在第3内含子放置了一个loxP位点。体外的cre重组酶去除掉了目标ES细胞克隆中的floxed hygromycin cassette。接下来，exons 2和3被留作loxP位点的边界。这些小鼠与去甲基化突变株杂交，以确认重组等位基因具有无表型特征。（来源：J:93140）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
