Exon 2,对应2-52位的氨基酸,被替换成了带有IRES-lacZ和floxed PGK-neo元件的序列。 Western blot结果显示这些突变体中没有检测到蛋白质(来源:J:93035)
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Exon 2, corresponding to amino acids 2-52, was replaced with an IRES-lacZ and floxed PGK-neo cassette. Western blot showed lack of protein in mutants. (J:93035)