一种新霉素抗性基因替换了包括ATG前9bp上游区域以及部分内含子1的exon 1。对突变小鼠视网膜的 Western blot 检测显示没有蛋白质表达。(来源:J:93040)
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A neomycin resistance gene replaced exon 1, including 9 bp upstream of the ATG, and part of intron 1. Western blot of retinas from mutant mice indicated no protein was present. (J:93040)