Cre重组酶剪除了包含3和4号外显子的敲除区域,这个区域编码了细胞外和跨膜部分,以及部分胞质区。RT-PCR没有在突变体中检测到mRNA。流式细胞术分析显示突变脾细胞没有表面表达。(来源:J:92732)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
基因内删除
--
1
3
26

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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