将编码缺失了85个氨基酸的细胞质基质域末端79个氨基酸的鼠IL-2受体γ链cDNA插入到一个包含5kb5'上游序列(包括启动子、转录起始位点和第一个内含子),以及5.5kb3'下游序列(包括人类CD2基因的调控区)的表达载体中。转基因产物在CD4+ CD8+胸腺细胞和脾脏及外周血T淋巴细胞中表达。(来源:J:92739)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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