将含有pKOS-lacZ/MC1neo(lexicon genetics, woodlands, tx)的基因陷阱载体插入,用于取代该基因的前四个外显子。在血小板、肺、肌肉和脂肪细胞中的 Western blot 检测并未发现蛋白质。(来源:J:92404)
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A gene trap vector containing pKOS-lacZ/MC1neo (Lexicon Genetics, Woodlands, TX) was inserted to replace the first four exons of the gene. Western blot analysis on platelets, lung, muscle and adipocytes did not detect protein. (J:92404)