Dspd

A transgene insertion resulted in a translocation between chromosomes 7F and 14C and a deletion on chromosome 7C of at least 1 Mb. This deletion contains at least 6 genes including; Cttn, Fadd, Fgf3, Fgf4, Fgf15, and Ccnd1. The transgene contained a chicken Actb promoter, CMV-IE enhancer and a full length human PEG8 cDNA. Expression of the transgene is not thought to be involved in this phenotype. (J:89381)