Exon 5,所有不同剪接转录本都共有的第一个外显子,在插入neo后被中断。Southern blot证实了重组,Northern blot未检测到野生型或剪切片段的转录本。Western blot确认了没有检测到任何蛋白质,不论是完整还是部分的。(来源:J:91590)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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