Log In|Sign Up
中文
将nLacZ基因和一个由loxP位点引导的诺卡因抗性基因座替换了编码信号序列及大部分丰富半胱氨酸结合域的1-125号密码子。PCR确认了neo基因的整合，且未检测到内源序列，通过突变皮肤的X-gal染色显示了基因的表达。 Western blot针对内源基因的C端17个氨基酸进行检测，结果显示在突变皮肤中未检测到。随后，通过与携带germ-line Cre基因的实验鼠杂交，去除了floxed neo。(来源：J:91412)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
