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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(KRT5-cre)5132Jlj
Alias:
K5-Cre
K5Cre 5132
K5Cre
K5 Cre
Tg.K5Cre
Tg(KRT5-cre)1Armz
BK5-Cre
K5
cre
K5Cre5132
Tg(KRT5-cre)1Jlj
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基础信息
表型特征
文献报道
这个转基因包含了牛KRT5调控元件,驱动nis-cre基因的表达。在这个品系中,只有一条转基因。Cre表达出现在分层上皮中。当转基因在雌性中存在时,不论是否通过cre转基因遗传,所有后代都会经历普遍的Cre介导重组。(来源:J:89783)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3050065
(C57BL/6J x DBA/2J)F2
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130
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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