在Xist基因5.5至8千碱基上游,包括Rps12-ps1的2.5千碱基序列被删除,这个区域被认为包含Xist的一个上游启动子。同时插入了floxed PGK-neo标记。逆转录PCR结果显示,突变体中存在野生型中不存在的Xist上游反义转录。(来源:J:85305)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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