这个转基因包含了酵母上游激活序列(UAS),驱动表达的是完整的murine Shh基因全长序列。转基因的表达依赖于GAL4的表达。只产生了一条在中枢神经系统中因GAL4表达诱导Shh表达的转基因小鼠线(来源:J:57948)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x CBA/J)F1
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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