Exon 1,编码1到132个氨基酸,被替换了 neoventa 选择标记。对成年纯合小鼠所提取的胰蛋白酶原进行 Western blot 分析,结果显示这个等位基因未检测到表达出任何可识别的蛋白质。(来源:J:74654)
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Exon 1, encoding residues 1-132, was replaced by a neomycin selection cassette. Western blot analysis on zymogen granules derived from adult homozygous mice confirmed that no detectable protein was expressed from this allele. (J:74654)