使用单一导向构建替换了Gstp1基因的第6和7外显子,以及Gstp2基因的全部编码序列,用的是en2A-IRES-betageo cassette。Northern和Western印迹分析证实了Gstp1转录物和编码蛋白的缺失。(来源:J:47638)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intergenic deletion
--
1
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24

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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