外显子4和部分外显子5,包括起始密码子和CARD区域的编码,被替换了 neo cassette。脾细胞的 Western blot 显示突变动物中没有蛋白质。(来源:J:84036)
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Exon 4 and part of exon 5, including the start codon and the code for the CARD region, were replaced with a neo cassette. Western blot of splenocytes indicated absence of protein in mutant animals. (J:84036)