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中文
这个等位基因在Imu-Cmu内含子中有一个大约4.6kb的缺失。通过Cre介导的重组，移除了内含子中的一个被修饰的neo，留下一个loxp序列。纯合突变体的IgG1、IgG3和IgA表面表达减少了5到20倍，与野生型相比，IgG2b和IgG2a的表达减少了2到5倍。IgM的表达未见改变。(来源：J:90548)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
