在cDNA序列的35-256位插入了一个neo,替换了部分exon 1和全部exon 2。 Western blot结果显示突变巨噬细胞中没有蛋白质表达。(来源:J:90980)
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A neo was inserted to replace part of exon 1 and all of exon 2, corresponding to base pairs 35-256 of the cDNA sequence. Western blot indicated absence of protein in mutant macrophages. (J:90980)