通过同源重组引入了四核苷酸变化,导致两个氨基酸替换(15位G变为R,151位V变为M),以及插入了IRE斯-tauGFP基因。产生的蛋白质是Olfr151和Olfr160的杂交体,它们总共有25个碱基和11个氨基酸差异。GFP基因在终止密码后融合,并与突变蛋白一起表达。(来源:J:90716)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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