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中文
Cre介导的重组移除了Kittm3Bsm中的floxed neo，留下一个位于第9 intron的单个loxP位点，以及酪氨酸567至苯丙氨酸的突变。流式细胞术显示受体水平降低到正常水平的50-60%，RNA保护实验表明转录本也减少了50-60%，这推测可能意味着突变体中9号内含子的剩余lox位点和周边序列影响了RNA的转录和/或剪接(来源：J:90485)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
