Exons encoding the N-terminal region were replaced with a pMC1-neo cassette via homologous recombination. Northern blot and in situ analysis confirmed the absence of mRNA expression in homozygotes. (J:89818)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count